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A portfolio of products to benefit a variety of patients.

Our Products

We aspire to be a leader in oral health by developing products that make a meaningful difference in patients’ lives.

Advancing Oral Health...
Improving Overall Health™

OraPharma offers a comprehensive suite of products to address a range of patient concerns – from the foundation of gums, bone, and teeth, to the aesthetics of a whiter smile.


Our flagship product, ARESTIN® (minocycline hydrochloride) Microspheres, 1 mg, is indicated as an adjunct to scaling and root planing (SRP) procedures for reduction of pocket depth in patients with adult periodontitis. Clinical studies show that ARESTIN® plus SRP achieves greater pocket depth reduction than SRP alone.

Using advanced microsphere technology, ARESTIN® provides sustained release of minocycline, a broad-spectrum antibiotic that targets infection. Currently, ARESTIN® is the leading locally administered antibiotic (LAA) for the treatment of periodontitis.

Clinical trial data demonstrate clear benefits from active treatment with ARESTIN® plus SRP when indicated to:

  • Create a healthier environment for healing
  • Target the microorganisms associated with a periodontal infection
  • Significantly reduce pocket depth compared to SRP alone
  • Help restore a state of periodontal health

For more information and Important Safety Information about ARESTIN®, please see below or visit (for patients) or (for professionals).
To order, please contact Customer Service at 1-866-273-7846.


Our portfolio also includes OSSIX® PLUS resorbable membrane, manufactured by Datum Dental Ltd., a collagen dental membrane for Guided Bone Regeneration (GBR) and Guided Tissue Regeneration (GTR). The unique, patented GLYMATRIX™ cross-linking technology provides OSSIX® PLUS the ability to maintain barrier functionality for 4-6 months, allowing sufficient time for osseous defects to achieve optimal bone regeneration. The membrane has excellent handling properties and readily adapts and conforms to defects. Without need to tack or suture, it has dual-sided usage. The collagen is porcine-derived, providing excellent biocompatibility.

For additional information about OSSIX® PLUS, please read the Instructions for Use.
To order, please contact Customer Service at 1-866-273-7846.

EZ White® Pro

OraPharma also offers EZ White® Pro In-Office Whitening System, the professional teeth whitening solution that’s easy to incorporate in dental practices and easy on patients. It’s fast, mild, and effective to give patients smiles up to 8 shades whiter in as little as 30 minutes.

Learn more about EZ White® Pro In-Office Whitening System
To order, please contact Customer Service at 1-866-273-7846.

ARESTIN® Indication & Important Safety Information

ARESTIN® (minocycline hydrochloride) Microspheres, 1 mg is indicated as an adjunct to scaling and root planing (SRP) procedures for reduction of pocket depth in patients with adult periodontitis. ARESTIN® may be used as part of a periodontal maintenance program, which includes good oral hygiene and SRP.

ARESTIN® should not be used in any patient who has a known sensitivity to minocycline or tetracyclines. The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of the teeth, and therefore should not be used in children or in pregnant or nursing women. Hypersensitivity reactions that included, but were not limited to, anaphylaxis, angioneurotic edema, urticaria, rash, swelling of the face and pruritus have been reported with the use of ARESTIN®. In clinical trials, the most frequently reported nondental treatment-emergent adverse events were headache, infection, flu syndrome and pain.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit, or call 1-800-FDA-1088.