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References:

  1. Page RC. Periodontal diseases: a new paradigm. J Dent Educ 1998;62:812-821.
  2. Williams RC. Periodontal disease. N Engl J Med 1990;322:373-382
  3. US Department of Health and Human Services. First-ever surgeon general's report on oral health finds profound disparities in nation's population.
    www.surgeongeneral.gov/news/pressreleases/pr_oral_52000.htm. Accessed December 11, 2007.
  4. ARESTIN® (minocycline hydrochloride) 1 mg Microspheres [Prescribing Information]. Warminster, PA: OraPharma, Inc.; 2005.
  5. 5. Goodson JM, Gunsolley JC, Grossi SG, et al. Minocycline HCl microspheres reduce red-complex bacteria in periodontal disease therapy. J Periodontol 2007;78(8):1568-1579.
  6. Doherty F, Lessem J, Hanlon A, Rose T. Efficacy of arestin in perio-maintenance patients. J Clin Periodontol 2003;30(suppl 4):19-100.
  7. Williams RC, Paquette DW, Offenbacher S, et al. Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol 2001;72:1535-1544.

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